Would deleting as many files/folders from a linux server speed things up from the perspective of logic?

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http://stackoverflow.com – In a real world situation the more un-necessary stuff you remove from a car the faster it runs. once i create a cloud server that runs "centos 6.2" for example.. i notice the file system has a-lot of folders that do not need to be there in order for the web site to be operational. should all those folders be removed? what would be the impact on the performance of the web site is it measurable at all ? is it measurable somehow? (HowTos)