Why so many apache slots marked as "busy"?

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http://serverfault.com – During the month of May there was a spike in the amount of busy apache slots. What could have caused this spike? If you look at Google Analytics (included below) there isn't really a change of traffic during May. I also included the mysql graph to show that I enabled mysql caching at one point but I doubt it would cause more busy apache process. Question What could have caused this busy server spike? Stats Apache process: http://i.imgur.com/cMthh.png Mysql: http://i.imgur.com/vg6fj.png Google Analytics: http://i.imgur.com/yl8Ui.png (HowTos)