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What is the best way to find a list of several strings within a large text file

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http://unix.stackexchange.com – The short, general question is: In Unix/Linux, what is the best way to find a list of several (about 150) strings within a large text file? I am asking this to all Unix/Linux experts as a general question, in the hopes that I can find a solution that pertains to my particular case: I have a feeling this is going to take a little tinkering. I have a large text file (actually, an MVS dataset) on an IBM Unix System Services (USS) machine-- I believe it is somewhere around 6GB. I also have a list of about 150 5-character identifiers in the format AAAAA that I need to find within this file-- tha (HowTos)