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Should I keep my Outlook OST files on a seperate Drive on my Terminal Server?

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http://serverfault.com – Should I keep my Outlook OST files on a seperate Drive on my Termial Server? I'm running a Windows 2003 Server with Outlook 2010. I can install the Operating Systems, Programs, and have user's Outlook files on the C: drive, or I can install a seperate drive and put the OST files there. We are using a third-party host that we connect over comcast bussiness-class internet, with a 1.6Ghz Xeon processor with 4GB Ram. 4 to 6 users durring bussiness hours runing Outlook always open and and other running other programs. (HowTos)