Server 2012, Jumbo Frames - should I expect problems?

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http://serverfault.com – Ok, this sound might stupid - but is there any negative on just enabling jumbo frames in practice? From what I understand: Any switch or ethernet adapter that sees a jumbo frame it can not handle will just drop it. TCP is not a problem as max frame size is negotiated in the setinuo phase. UCP is a theoretical problem as a server may just send a LARGE UDP packet that gets dropped on the way. Practically though, as UDP is packet based, I do not really think any software WOULD send a UDP packet larger than 1500 bytes net without app level configuration changes - at least this is how I do my (HowTos)