postfix relay access denied

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http://serverfault.com – I am getting relay access denied when I try sending e-mail via out look on my pc using postfix on my vps. I read this could be a problem with mydestination but that all looks to be setup correctly. postconf -n [root@mydomain ~]# postconf -n alias_database = hash:/etc/aliases alias_maps = hash:/etc/aliases command_directory = /usr/sbin config_directory = /etc/postfix daemon_directory = /usr/libexec/postfix data_directory = /var/lib/postfix debug_peer_level = 2 home_mailbox = Maildir/ html_directory = no inet_interfaces = all inet_protocols = al (HowTos)