is it possible to host 2 sites on a single domain but 2 different IPs?

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http://serverfault.com – I have Server A which hosts www.mysite.com I want to create and host a site on Server B, but configure it to: www.mysite.com/theSiteAtServerB TheSiteAtServerB is a completely different site from www.mysite.com and is on a completely different server but the client wants to use www.mysite.com and serve the content for TheSiteServerB under the same url. Is this at all possible? DNS configuration? or through some Apache magic? Thank you! EDIT 1: To clarify, I would like to achieve this without redirecting or rewriting urls. http://www.mysite.com/ & http://www.mysite.com/site (HowTos)