is it better to run linux distros live or installed on virtual box

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http://askubuntu.com – i want to run and install some applications too on my Linux distributions on the virtual box. so what is better 'live' versions or full installs on the Virtual box. and what is the difference between the two(regarding features and required configurations) i use, toshiba satellite p755-s5215; mem- 5 Gib; proc- intel i3; cpu- 2.10GHz; graphics-sandybridge mobile; OS- 64 bit; (HowTos)