How to run programs in a Sandbox?

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http://unix.stackexchange.com – I have been using PlayOnLinux to run windows programs on Linux. PlayOnLinux creates a virtual drive for each program installed and every VD represents a different Windows XP computer. Any changes made by the program stay within its own VD only. So if I run a program with a virus I can simply delete the program's VD and all is well. Is there a similar program that allows Linux programs to be run in a virtual drive? i.e. I want PlayOnLinux/Wine minus the windows emulation. (HowTos)