How to configure dnsmasq to forward multiple DNS servers?

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http://serverfault.com – I'm now using public DNS over VPN to avoid some DNS pollution in China. But this come with a price that I can't take advantage of CDN. Is there a way to configure dnsmasq and let it query both DNS servers, both public one and ISP one, and return the IP with a lower metric? I knew it could be done by using server=/domain/server directive to assign a DNS server for a certain domain, but the problem is there are hundreds of them. So I have to figure out something generic. Thanks in advance. (HowTos)