F16 eol, f17->f18

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http://forums.fedoraforum.org – I'm just writing to ask about the upgrade path from F16->F17->F18 How likely is it to cause problems? How much manual maintenance could be envisioned I might need to do (I understand that this would vary with the currently installed packages I have). Is there anything considerably different that I should know about? Finally, if I were to decide it is too hassle-some to upgrade all my workstations, would there be any serious consequences to not doing so? I understand that these are fairly hand-wavy questions that can't necessarily be answered without some certain information from me (HowTos)