Exchange 2010 CAS and Edge-Transport on VPS in datacentres

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http://serverfault.com – I have a central office site and I would like to know if it is considered acceptable to install Exchange 2010 CAS/Edge-Transport roles on VPS(s) in external datacentre(s) with a VPN back to our HQ where our mailbox and hub servers are. My main goal is to have mail queued should the main site go down due to a local ISP failure. Would there be any issues with this design and anything to be aware of? (HowTos)