Does RHEL 6 enforce software constraints on the number of SATA drvices that can exist on a system?

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http://unix.stackexchange.com – I came across the following blurb in some RHEL 6 training documentation: The number of drives that can be installed on modern computers has increased. With port multipliers, it's relatively easy to configure 16 Serial Advanced Technology Attachment (SATA) drives on a system (assuming you can fit all of those drives). Does this mean that RHEL 6 won't allow more than 16 SATA drives from a software perspective? Or just that practical hardware constraints usually don't allow for more than 16 but it's technically possible? (HowTos)