django, mod_wsgi, MySQL High CPU - Problems

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http://serverfault.com – Good Evening, and thank you for reading this post. I am having a problem with Django after migrating the dB from SQLlite to MySQL. Initially, for the first 48hours, all ran well. But now we are experiencing high cpu about every 30 minutes. This is a production ESX4i VM host, with 2 x 2.8 ghz CPUs and 12 GB ram. I have allocated 4 cpu's to this VM and 4 GB memory. Any insight into this configuration and help with the spikes in CPU would be appreciated. IT is configured to use the prefork MPM. Outlined are the config's for the different services: MySQL Server version: 5.1.61 Source distribu (HowTos)