Control outbound connections in postfix

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http://serverfault.com – I have a postfix server that i use to send auto responders and newsletters to subscribers. I know that major ISP's like hotmail and yahoo look for how many connections they get from an ip address. SO i want to know the following 1. how many connection does a postfix server opens ? 2. how many emails per connection does a postfix server send ? 3. how can i control the amount of connections to a specific ISP ? Thanks (HowTos)