Can I safely sync .config/ between computers?

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http://askubuntu.com – I have a netbook and desktop which I'd like to share application configuration between through Dropbox. Currently my netbook is set to symlink ~/.config -> ~/Dropbox/.config which it's working fine. I'm about to add this setup to my desktop but thought I'd ask about it first. Is it safe to sync ~/.config/ between computers? (HowTos)