I've been having the same problem since switching to 3.8. It seems like an upstream bug. The best workaround I have is to plug the mouse out and back in when it freezes.
on 04/09/2013 – Made popular on 04/09/2013
I'm having an issue in Kubuntu (also tried in Mint with Cinnamon and Arch with kde/kdm) where, upon login, I can move my (USB) mouse for about 5 seconds. After that, my mouse freezes and will not move; mouse buttons do not work either. If I unplug it and plug it back in, it does not even light up. I've tried other USB ports on the computer, which do not work either.
I have a Acer Aspire 5750, I had recently bought the HP X1000 Wired Mouse. The problem is that the mouse isn't working on this laptop, I had installed all the drivers and plugged the USB in all three of the laptop's ports. I know that the mouse isn't faulty since I tested the mouse on another laptop and there were no problems.